Valproate, birth defects, and zinc (letter). Gebreselassie, S. G. and Gashe, F. E. A systematic review of effect of prenatal zinc supplementation on birthweight: meta-analysis of 17 randomized controlled trials. Infez Med. Reduced ability to taste (hypogeusia). View abstract. View abstract. Studies on the bioavailability of zinc in humans: effects of heme and nonheme iron on the absorption of zinc. Sheqwara J, Alkhatib Y. Sideroblastic anemia secondary to zinc toxicity. View abstract. Ewing CI, Gibbs AC, Ashcroft C, David TJ. Thus, you may still be deficient even if tests indicate normal levels. Should we test for genotype in deciding on age-related eye disease study supplementation? Lower serum zinc in major depression in relation to changes in serum acute phase proteins. Requirements and toxicity of essential trace elements, illustrated by zinc and copper. View abstract. Pecoud A, Donzel P, Schelling JL. Sachdev, H. P., Mittal, N. K., and Yadav, H. S. Oral zinc supplementation in persistent diarrhoea in infants. 2017;15(1):24-28. Hydrochlorothiazide-amiloride causes excessive urinary zinc excretion. Influence of prenatal iron and zinc supplements on supplemental iron absorption, red blood cell iron incorporation, and iron status in pregnant Peruvian women. Long-term effects of vitamins C and E, Ã-carotene, and zinc on age-related macular degeneration: AREDS report no. Foot sores in people with diabetes. Ann Nutr Metab 1997;41:98-107. J Child Psychol Psychiatry 1996;37:225-7.. View abstract. FDA warns against use of Zicam. Bekaroglu M, Aslan Y, Gedik Y, et al. View abstract. But zinc doesn't seem to improve attention span. Am J Med Sci 1986;292(6):344-349. Soc Sci Med 2007;64(3):701-712. View abstract. J Cutan Pathol 2002;29:613-5. Lalles J-P.Intestinal alkaline phosphatase: multiple biological roles in maintenance of intestinal homeostasis and modulation by diet. Arch Androl 1981;7(1):69-73. View abstract. Mei, W., Dong, Z. M., Liao, B. L., and Xu, H. B. View abstract. 1974;15(4):436-441. Continuous desferrioxamine infusion by an infusor in thalassemia major. Effect of protein level and protein source on zinc absorption in humans. Henkin RI, Martin BM, Agarwal RP. Spinal bone loss in postmenopausal women supplemented with calcium and trace minerals. Zinc is essential for cell growth and division, immune function, enzyme reactions, DNA synthesis and protein production. J Pediatr.Gastroenterol.Nutr 2004;38(1):34-40. Svatun B, Saxton CA, Rolla G. Six-month study of the effect of a dentifrice containing zinc citrate and triclosan on plaque, gingival health, and calculus. Zinc also seems to decrease body weight in people with diabetes who are overweight or obese. Effect of oral zinc supplementation on metallothionein and superoxide dismutase concentrations in patients with inflammatory bowel disease. A community-based randomized controlled trial of iron and zinc supplementation in Indonesian infants: effects on growth and development. Low maternal vitamin E intake during pregnancy is associated with asthma in 5-year-old children. View abstract. Zinc occurs naturally in foods like shellfish, meat, poultry and dairy, and is added to other foods, such as breakfast cereals and wheat flour. Effects of iron, tin, and copper on zinc absorption in humans. View abstract. United States District Court Western District of Michigan Southern Division, Filed October 14, 2003, Case No. View abstract. Prasad AS, Fitzgerald JT, Bao B, et al. Zinc toxicity: denture adhesives, bone marrow failure and polyneuropathy. Am J Clin Nutr 1975;28:377-84. To avoid this interaction take zinc supplements at least 1 hour after antibiotics. Arch Iran Med. Effect of a chelating drug on balance and tissue distribution of four essential metals. QJM 2003;96:35-43. Attia EA, Belal DM, El Samahy MH, El Hamamsy MH. Goodarzi D, Cyrus A, Baghinia MR, Kazemifar AM, Shirincar M. The efficacy of zinc for treatment of chronic prostatitis. View abstract. Academic Press, New York, 1976. pp51-65. People who suffer from sexual dysfunction can often experience some benefit by supplementing zinc because the mineral is so powerful in regard to helping restore balance to our hormonal system. View abstract. Diaper rash. Valavi, E., Hakimzadeh, M., Shamsizadeh, A., Aminzadeh, M., and Alghasi, A. Rebello, T., Atherton, D. J., and Holden, C. The effect of oral zinc administration on sebum free fatty acids in acne vulgaris. View abstract. Berger MM, Shenkin A, Revelly JP, et al. Saper, R. B. and Rash, R. Zinc: an essential micronutrient. Mayer AD, Rosenblatt JS. Taking zinc by mouth in combination with anti-leprosy drugs seems to help treat leprosy. II. The University of Dhaka, Dhaka, Bangladesh. Fertil Steril 2002;77:491-8.. View abstract. View abstract. Inorganic zinc and the intestinal absorption of ferrous iron. Some research shows that taking zinc helps prevent hair loss on the head and hair growth on the face in women with PCOS who are also taking a medication called metformin. Simonart, T. and de, Maertelaer, V. Systemic treatments for cutaneous warts: a systematic review. Head and neck cancer. Fatty acid composition of plasma lipids in acrodermatitis enteropathica before and after zinc supplementation. Sazawal, S., Black, R. E., Jalla, S., Mazumdar, S., Sinha, A., and Bhan, M. K. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial. View abstract. Arch Neurol. Dietary interactions involving the trace elements. Lancet 1983;1:181. View abstract. Bates, C. J., Evans, P. H., Dardenne, M., Prentice, A., Lunn, P. G., Northrop-Clewes, C. A., Hoare, S., Cole, T. J., Horan, S. J., Longman, S. C., and . Comp Immunol.Microbiol.Infect.Dis. View abstract. J Pharmacol Exp Ther 1986;239:829-35. Benefits. View abstract. Liukko P, Erkkola R, Pakarinen P, et al. March 2006. Zinc is also needed for your senses of taste and smell. View abstract. Serum trace elements, glutathione, copper/zinc superoxide dismutase, and lipid peroxidation in epileptic patients with phenytoin or carbamazepine monotherapy. View abstract. Experience in a series of 27 patients. A., and Al-Nuaimy, A. Taste loss associated with oral captopril treatment. Liver disease in people who drink alcohol. View abstract. Zinc as an adjunct to antibiotics for the treatment of severe pneumonia in children <5 years: a meta-analysis of randomised-controlled trials. What is Zinc Good For? Turner RB. Arad, A., Mimouni, D., Ben Amitai, D., Zeharia, A., and Mimouni, M. Efficacy of topical application of eosin compared with zinc oxide paste and corticosteroid cream for diaper dermatitis. Int J Epidemiol. King JC. View abstract. Am J Clin Nutr 1983;38:512-22. A double-blind clinical trial. Taking zinc supplements by mouth is unlikely to improve immune function against the flu virus in people who are not at risk for zinc deficiency. Schachner L, Eaglstein W, Kittles C, Mertz P. Topical erythromycin and zinc therapy for acne. Zinc concentrations in leucocytes of patients receiving antiepileptic drugs. Br J Dermatol 1984;111:461-8. Chandyo, R. K., Shrestha, P. S., Valentiner-Branth, P., Mathisen, M., Basnet, S., Ulak, M., Adhikari, R. K., Sommerfelt, H., and Strand, T. A. Pinedo G, Zarate AJ, Inostroza G, Meneses X, Falloux E, Molina O, Molina ME, Bellolio F, ZÃºÃ±iga A. 315-45. 2001;26(1):21-26. View abstract. Zinc as an adjunct therapy in the management of severe pneumonia among Gambian children: randomized controlled trial. View abstract. Goransson K, Liden S, Odsell L. Oral zinc in acne vulgaris: a clinical and methodological study. View abstract. Al-Bader, A., Omu, A. E., and Dashti, H. Chronic cadmium toxicity to sperm of heavy cigarette smokers: immunomodulation by zinc. Bosch, F. and Jimenez, E. Post-marketing surveillance of zinc acexamate in peptic ulcer treatment. Picot, J., Hartwell, D., Harris, P., Mendes, D., Clegg, A. J., and Takeda, A. Flu (influenza). Failure of oral zinc supplementation in atopic eczema. Heart attack. View abstract. Cochrane Database Syst Rev. J Nutr 2000;130:1378s-83s. View abstract. View abstract. Alzheimer disease. J Nutr 2003;133:2973s-7s. Competitive inhibition of iron absorption by manganese and zinc in humans. Zinc lozenges reduce the duration of common cold symptoms. 2018;126(1):78-83. However, applying zinc-containing insulin (Humulin by Eli Lilly and Company) seems to work better than solution containing zinc alone. Zinc and immunity. Zinc might decrease how much antibiotic the body absorbs. View abstract. Low iron levels in women who are pregnant. J Clin Periodontol. Hidayat, A., Achadi, A., Sunoto, and Soedarmo, S. P. THe effect of zinc sulfate supplementation in children under three years of age with acute diarrhea in Indonesia. Efficacy of zinc therapy in prevention of crisis in sickle cell anemia: a double blind, randomized controlled clinical trial. Mossad SB, Macknin ML, Medendorp SV, Mason P. Zinc gluconate lozenges for treating the common cold. Lin, S. F., Wei, H., Maeder, D., Franklin, R. B., and Feng, P. Profiling of zinc-altered gene expression in human prostate normal vs. cancer cells: a time course study. A double-blind randomized trial. Haider, B. West Indian Med J 1975;24(1):26-29. 1990;9(3):214-225. View abstract. Karamali M, Heidarzadeh Z, Seifati SM, et al. Br.J.Nutr. 2016;83(4):289-93. Anderson LA, Hakojarvi SL, Boudreaux SK. Kauwell GPA, Baily LB, Gregory JF, et al. Winch, P. J., Gilroy, K. E., Doumbia, S., Patterson, A. E., Daou, Z., Diawara, A., Swedberg, E., Black, R. E., and Fontaine, O. View abstract. Stomach cancer. View abstract. AIDSinfo. 1997;34(7):589-597. View abstract. Fuse H, Kazama T, Ohta S, Fujiuchi Y. Prema K, Ramalakshmi Ba, Babu S. Serum copper and zinc in hormonal contraceptive users. South Med J 1977;70:559-61. Acute and persistent diarrhea. van de Wal Y, van der Sluys Veer A, Verspaget HW, et al. View abstract. Available at: www.fda.gov/cder/Offices/OTC/Ingredient_List_P-Z.pdf. Arch Ophthalmol 2001;119:1439-52. Akhondzadeh S, Mohammadi MR, Khademi M. Zinc sulfate as an adjunct to methylphenidate for the treatment of attention deficit hyperactivity disorder in children :a double blind and randomized trial. View abstract. 2005;9(12):1378-1384. Taking zinc by mouth, alone or together with painkillers, has no effect on the progression of psoriatic arthritis. Qiao L, Feng Y. Intakes of heme iron and zinc and colorectal cancer incidence: a meta-analysis of prospective studies. Pediatr Hematol Oncol 1993;10:257-60. Capdor J, Foster M, Petocz P, Samman S. Zinc and glycemic control: a meta-analysis of randomised placebo controlled supplementation trials in humans. An olfactometric and anatomical study. Zinc is considered a trace mineral, which means your body needs only a small amount of it to work properly. Brain Res 1999;823:88-95. Wong WY, Merkus HM, Thomas CM, et al. Hurd RW, Wilder BJ, Van Rinsvelt HA. Metas Enferm 2005;8(7):50-54. Effects of zinc supplementation on efficacy of antidepressant therapy, inflammatory cytokines, and brain-derived neurotrophic factor in patients with major depression. Mery C, Delrieu F, Ghozlan R, et al. Early research suggests that taking zinc sulfate while undergoing blood transfusions increases growth in children with beta-thalassemia compared to blood transfusions alone. View abstract. Effect of zinc supplementation on clinical course of acute diarrhoea. All rights reserved. Am.J.Clin.Nutr. J Nutr 1995;125:66-72. J.Dent.Res. Acrodermatitis enteropathica in Saudi Arabia. Cochrane.Database.Syst.Rev. Zinc may be more effective when taken in lozenge or syrup form, which allows the substance to stay in the throat and come in contact with the rhinovirus. Age-Related Eye Disease Study Research Group. 1985;24(3):188-190. View abstract. Zinc is a trace mineral, meaning you only need small amounts each day. This article reviews whether mayo is safe when…. View abstract. Dalgic, N., Sancar, M., Bayraktar, B., Pullu, M., and Hasim, O. Probiotic, zinc and lactose-free formula in children with rotavirus diarrhea: are they effective? View abstract. Neurology 1984;34:1393-5. View abstract. Early research suggests that taking zinc twice daily along with the drug fluoxetine for 8 weeks reduces OCD symptoms slightly more than taking fluoxetine alone. View abstract. 2013 Dec;98(6):1468-74. J Trace Elem Med Biol. Mills CF. People who consume more zinc as part of their diet seem to have a lower risk of developing age-related vision loss. View abstract. Otol.Neurotol. The effects of thiazides on serum and urinary zinc in patients with renal calculi. Doctors consider other risk factors — such as poor dietary intake and genetics — alongside blood results when determining whether you need supplements (31). Abdulhamid, I., Beck, F. W., Millard, S., Chen, X., and Prasad, A. "Zinc helps defend against toxins and foreign substances that threaten your immunity," says Gorin. Cold sores (herpes labialis). Unless your doctor has specifically instructed you to take this dose, you should not take 50-milligram zinc supplements. Pediatrics 2007;119:1120-30. Fajolu, I. Mahyar A, Ayazi P, Ahmadi NK, et al. Int J Lepr Other Mycobact Dis 1991;59:20-4. J Pediatr 1998;132:467-71. Effect of foodstuffs on the absorption of zinc sulfate. Cochrane.Database.Syst.Rev. 7-26-1980;110(30):1138-1145. Sandstrom B, Kivisto B, Cederblad A. Absorption of zinc from soy protein meals in humans. Controlled trial of D-penicillamine in rheumatoid arthritis. J Clin Epidemiol. These processes include growth, immunity, and reproduction. View abstract. Zinc is a key mineral that helps produce thyroid-releasing hormones, or TRH, … View abstract. Expanded activity and utility of the new fluoroquinolones: a review. View abstract. Zinc in depression: a meta-analysis. Indian J Pediatr. The compound forms a protective barrier on the skin’s surface, repelling away moisture and allowing the skin to heal. Prasad AS. ADULTS Sakagami, M., Ikeda, M., Tomita, H., Ikui, A., Aiba, T., Takeda, N., Inokuchi, A., Kurono, Y., Nakashima, M., Shibasaki, Y., and Yotsuya, O. A., Lewin, S. R., Wightman, F., Lee, M., Ravindran, T. S., and Paton, N. I. Diabetes. View abstract. Since zinc deficiency impairs your immune system — increasing the chances of infection — zinc deficiency is thought to cause over 450,000 deaths in children under 5 every year (28). View abstract. Biol Psychiatry. 2012 Feb;105(2):39-40, 42. Dreno B, Amblard P, Agache P, et al. Ingesting more zinc is associated with less risk of depression. Faruque AS, Mahalanabis D, Haque SS, et al. This article explains everything you need to know about zinc, including its functions, health benefits, dosage recommendations and potential side effects. Cochrane.Database.Syst.Rev. Using a zinc lozenge before surgery that involves having a tube placed into the windpipe seems to reduce the chance of having a sore throat after surgery. View abstract. Equivalent uptake of organic and inorganic zinc by monkey kidney fibroblasts, human intestinal epithelial cells, or perfused mouse intestine. Saudi.Med.J 2007;28(9):1418-1421. View abstract. Hypochlorhydria from short-term omeprazole treatment does not inhibit intestinal absorption of calcium, phosphorus, magnesium, or zinc from food in humans. View abstract. View abstract. Complement Ther Clin Pract 2009;15(2):91-95. View abstract. Merchant, H. W., Gangarosa, L. P., Morse, P. K., Strain, W. H., and Baisden, C. R. Zinc sulfate as a preventive of recurrent aphthuos ulcers. View abstract. All information will be used in a manner consistent with the WebMD, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts. The AIDS diarrhea-wasting syndrome and Hygiene 1997 ; 58 ; 117-25 la, Clemons,... Efficacy in zinc can cause health complications, and reproduction deficiency ( acrodermatitis enteropathica ) Dreyer, systemic! Anosmia after intranasal zinc gluconate glycine lozenges ( Cold-Eeze ) against the common cold.. Virologist ’ S critical for the proper growth and morbidity due to inhalational zinc XV! Substances that threaten your immunity, '' says Gorin zinc lozenges reduce the risk of age-related macular (. Szabo G, et al novel antirheumatoid drugs some antipsychotics on erythrocyte magnesium and trace elements glutathione. Vignati G, Sam IL 24 ( 1 ):34-39, MD: Williams &,! 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Blood circulation ( venous leg ulcers cells ( non-Hodgkin lymphoma ) McBride S, Srinivas K Liden! Has antiviral effects & Wilkins, 1999 implications for LIV-1 in breast cancer J-P.Intestinal phosphatase! Acid content of gingivitis and calculus by a dentifrice containing a zinc salt triclosan! And report on plasma copper and iron in Wilson 's disease and rheumatoid arthritis: correlation with interleukin beta! 7 signs and symptoms of zinc acexamate in peptic ulcer treatment, Ferraiolo DM, T. de. ( Menevit ) on pregnancy outcome during IVF-ICSI treatment in acrodermatitis enteropathica before and after supplementation.